Ravulizumab is a long-acting terminal complement inhibitor that specifically binds to the complement protein C5 in the terminal complement...

Belimumab is a monoclonal antibody against B-cell activating factor (BAFF), and by blocking the B-cell activating factor, it interferes with B-cell...

A chimeric antigen receptor (CAR) is a cellular receptor engineered to connect an extracellular targeting function with intracellular domains that activate...

An acquired deficiency of the cytokine interleukin-2 (IL-2) and associated disturbances in regulatory T cell (Treg) homeostasis play a crucial role...

A chimeric antigen receptor (CAR) is a cellular receptor engineered to connect an extracellular targeting function with intracellular domains that activate...

Voclosporin is a calcineurin inhibitor which forms a heterodimeric complex with cyclophilin A, which binds to and inhibits calcineurin...

Mesenchymal stem cells (MSCs) are derived from bone marrow and are capable of differentiating into a variety of mesenchymal lineages and also possess...

ACTHar Gel is a long-acting formulation of adrenocorticotropic hormone. ACTHar gel binds to melanocortin receptors in a variety of cell types including...

ANX009 is an antigen binding fragment (Fab) of a humanized antibody against C1q that inhibits C1q substrate interactions and fully blocks activation...

Efgartigimod is a humanized IgG1 Fc fragment that binds to the neonatal Fc receptor and inhibits its interaction with IgG, thereby reducing IgG...

Zetomipzomib is a selective immunoproteasome inhibitor that specifically targets the inflammatory cells. The drug was shown to reduce the production...

Felzartamab is a fully human immunoglobulin G1 monoclonal antibody designed to target the highly expressed CD38 cell surface antigen on plasma cells...

Baricitinib is an oral selective inhibitor of Janus kinase 1 and 2. Previous studies have shown that baricitinib significantly reduced the concentration...

Obinutuzumab is a humanized, type II anti-CD20 monoclonal antibody that has a distinct mode of binding to the CD20 antigen compared with type I...

A chimeric antigen receptor (CAR) is a cellular receptor engineered to connect an extracellular targeting function with intracellular domains that activate...

A chimeric antigen receptor (CAR) is a cellular receptor engineered to connect an extracellular targeting function with intracellular domains that activate...

The aim of the study is to evaluate the efficacy of a therapeutic regimen which decreases glucocorticoid exposure compared with standard therapy...

Mesenchymal stem cells (MSCs) are derived from bone marrow and are capable of differentiating into a variety of mesenchymal lineages and also possess...

Obinutuzumab is a humanized, type II anti-CD20 monoclonal antibody that has a distinct mode of binding to the CD20 antigen compared with type I...

LNP023 is a small-molecule, oral, and selective inhibitor of factor B, a key component of the complement alternative pathway...

Ianalumab is a fully human monoclonal antibody that targets BAFF-Receptor. It has a novel dual mechanism of action: blockade of BAFF-R-mediated...

Daratumumab is a monoclonal antibody directed at CD38, which depletes CD38 expressing plasma cells in the bone marrow and a cell-type-specific...

Anifrolumab is a human monoclonal antibody to the type I interferon (IFN) receptor subunit 1, which blocks the action of type I IFNs...

Telitacicept (RC-18) is a novel, recombinant fusion protein, consisting of transmembrane activator and calcium modulator and...