People with homozygosity or compound heterozygosity for G1 and G2 risk alleles are at high risk of developing multiple kidney diseases...

Sparsentan is a novel single-molecule dual endothelin (ET-1) and angiotensin receptor antagonist with hemodynamic and anti-inflammatory...

Metfromin (MF) which is the most commonly used antidiabetic medications has been found to activate the AMP-activated protein...

Baricitinib inhibits Janus kinase (JAK) enzymes, which are intracellular enzymes involved in stimulating hematopoiesis and immune cell...

Familial FSGS has been associated with gain-of-function variants of the transient receptor potential cation channel, subfamily C...

Repagermanium is a C-C chemokine receptor type 2 (CCR2) inhibitor that, when administered concurrently with an angiotensin II receptor...