Atrasentan is an Endothelin A (ETA) receptor antagonist...

BION-1301 is a novel humanized anti-APRIL monoclonal antibody...

Some patients with IgAN have  lectin pathway activation...

Local complement activation in the mesangium...

Increased production of ET 1 has been associated with...

IONIS-FB-LRx is a ligand-conjugated (LICA) investigational antisense medicine...

Tegoprubart is a next generation monoclonal antibody...

Local activation of the alternative complement...